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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303035
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kif5a
Name: kinesin family member 5A
Acc ID: CHEBI:15422
Term: ATP
Definition: An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
Chemical ID: MESH:D000255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kif5aincreases hydrolysisISOKIF5A (Homo sapiens)6480464CTDKIF5A protein results in increased hydrolysis of Adenosine TriphosphatePMID:24239783
Kif5amultiple interactionsISOKIF5A (Homo sapiens)6480464CTDAdenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]; Egtazic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]]PMID:24239783 PMID:28122263
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