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GENE - TERM ANNOTATION REPORT

RGD ID: 1302993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ly96
Name: lymphocyte antigen 96
Acc ID: GO:0031663
Term: lipopolysaccharide-mediated signaling pathway
Definition: The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
Definition Source(s): GOC:mah, GOC:signaling, PMID:15379975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ly96acts_upstream_ofISOLy96 (Mus musculus)1624291RGDMGI:1194924 MGI:96824 PMID:10880523

PMID:10880523
Ly96involved_inISOLy96 (Mus musculus)1624291RGD MGI:5645195 PMID:24380872

MGI:5645195 PMID:24380872
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