GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ehmt2 | decreases expression | EXP | | 6480464 | CTD | sodium arsenite results in decreased expression of EHMT2 mRNA | PMID:30557709 | Ehmt2 | decreases expression | ISO | Ehmt2 (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of EHMT2 mRNA | PMID:28414027 | Ehmt2 | increases expression | ISO | EHMT2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of EHMT2 protein | PMID:27217333 | Ehmt2 | multiple interactions | ISO | Ehmt2 (Mus musculus) | 6480464 | CTD | sodium arsenite promotes the reaction [EHMT2 protein binds to CDKN2A promoter] | PMID:22733434 | Ehmt2 | multiple interactions | ISO | EHMT2 (Homo sapiens) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with BIX 01294] results in decreased expression of EHMT2 mRNA; [[sodium arsenite results in increased abundance of Arsenic] which co-treated with BIX 01294] results in decreased expression of EHMT2 protein; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of MPG mRNA; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of MPG protein; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of PARP1 mRNA; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of PARP1 protein; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of XRCC1 mRNA; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of XRCC1 protein; BRD4770 inhibits the reaction [sodium arsenite promotes the reaction [EHMT2 protein binds to PDK4 promoter]]; sodium arsenite inhibits the reaction [BRD4770 results in decreased expression of EHMT2 protein]; sodium arsenite promotes the reaction [EHMT2 protein binds to PDK4 promoter] | PMID:27217333 PMID:33378118 | |
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