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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1299953
Species: Homo sapiens
RGD Object: Gene
Symbol: ZEB1
Name: zinc finger E-box binding homeobox 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ZEB1decreases expressionISOZeb1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of ZEB1 mRNAPMID:33221593
ZEB1decreases expressionISOZeb1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ZEB1 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
ZEB1multiple interactionsISOZeb1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Genistein] results in decreased methylation of ZEB1 genePMID:28505145
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