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GENE - TERM ANNOTATION REPORT

RGD ID: 12612074
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: DOID:9005246
Term: Paralysis
Definition: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Definition Source(s): MESH:D010243
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
App ISOAPP (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:16122394 PMID:18762355 PMID:21706413 PMID:22952840 PMID:28915354 PMID:33290254 PMID:34902447
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