Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 12549326
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Rab14
Name: RAB14, member RAS oncogene family
Acc ID: PW:0000159
Term: Rab family mediated signaling pathway
Definition: Rab family mediated signaling pathways are involved in the regulation of intracellular vesicle trafficking. More than 60 Rab members bind to specific effectors to regulate all aspects of vesicular trafficking - from formation and transport of vesicles, to tethering and fusion with target membranes. Of note is that cytoskeletal rearrangements such as actin remodeling, a process regulated by Rho family, have a role to play in vesicular trafficking.
Definition Source(s): GO:0032482, PMID:11152757, PMID:16882731, PMID:18171430
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rab14 ISORGD:7371049068941RGD PMID:17629673, PMID:18171431, PMID:18570632, REF_RGD_ID:2302395, REF_RGD_ID:2302397, REF_RGD_ID:2306494
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.