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GENE - TERM ANNOTATION REPORT

RGD ID: 12539236
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Plat
Name: plasminogen activator, tissue type
Acc ID: GO:0031639
Term: plasminogen activation
Definition: The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
Definition Source(s): PMID:9548733
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plat ISOPlat (Rattus norvegicus)9068941RGD PMID:8343497 REF_RGD_ID:11537479
Platinvolved_inIEAUniProtKB:P00750 or ensembl:ENSP00000220809150520179Ensembl GO_REF:0000107
Platinvolved_inIEAInterPro:IPR026280150520179InterPro GO_REF:0000002
Platinvolved_inIEAPANTHER:PTHR24264:SF42150520179TreeGrafter GO_REF:0000118
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