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GENE - TERM ANNOTATION REPORT

RGD ID: 12458536
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Calm2
Name: calmodulin 2
Acc ID: PW:0001140
Term: calcium/calcium-mediated signaling pathway
Definition: Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis.
Definition Source(s): PMID:12838335, PMID:17574670, PMID:18083096, PMID:19243429
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Calm2 ISOCALM2 (Homo sapiens)9068941RGD PMID:10884684 PMID:18083096 REF_RGD_ID:7204676 REF_RGD_ID:7204677
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