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GENE - TERM ANNOTATION REPORT

RGD ID: 12430871
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL4R
Name: interleukin 4 receptor
Acc ID: DOID:635
Term: acquired immunodeficiency syndrome
Definition: A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/AIDS "DO" "DO", http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=aids "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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