Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 12426935
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CNOT6L
Name: CCR4-NOT transcription complex subunit 6 like
Acc ID: GO:0030014
Term: CCR4-NOT complex
Definition: The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.
Definition Source(s): GOC:sart, PMID:11113136, PMID:11239395, PMID:22785621, PMID:30601114
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CNOT6Lpart_ofIEAUniProtKB:Q96LI5 or ensembl:ENSP00000424896150520179Ensembl GO_REF:0000107
CNOT6Lpart_ofIEAPANTHER:PTHR12121:SF35150520179TreeGrafter GO_REF:0000118
Go Back to source page   Continue to Ontology report