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GENE - TERM ANNOTATION REPORT

RGD ID: 12422745
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: SUFU
Name: SUFU negative regulator of hedgehog signaling
Acc ID: GO:0045879
Term: negative regulation of smoothened signaling pathway
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SUFUinvolved_inIEAUniProtKB:Q9UMX1 or UniProtKB:Q9Z0P7 or ensembl:ENSMUSP00000107498 or ensembl:ENSP00000358918150520179Ensembl GO_REF:0000107
SUFUacts_upstream_of_or_withinISOMGI:36190469068941MGI PMID:16459298

PMID:16459298
SUFUacts_upstream_of_or_withinISOMGI:48404209068941MGI PMID:19684112

PMID:19684112
SUFUacts_upstream_of_or_withinISOSufu (Mus musculus)9068941MGI PMID:18488998

PMID:18488998
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