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GENE - TERM ANNOTATION REPORT

RGD ID: 12383470
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL10
Name: interleukin 10
Acc ID: DOID:12361
Term: Graves' disease
Definition: An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Graves_disease "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL10 ISOIL10 (Homo sapiens)9068941RGDDNA:SNP: :rs1800896 (human)PMID:21424183 REF_RGD_ID:7364858
IL10 ISOIL10 (Homo sapiens)9068941RGDDNA:SNPs:promoter:-1082A>G, -819C>T, -592C>A (human)PMID:19882211 REF_RGD_ID:7364862
IL10 ISOIL10 (Homo sapiens)9068941RGDprotein:increased expression:serumPMID:19250272 REF_RGD_ID:7365026
IL10no_associationISOIL10 (Homo sapiens)9068941RGDDNA:SNPs:promoter:multiplePMID:15497451 REF_RGD_ID:7365074
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