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GENE - TERM ANNOTATION REPORT

RGD ID: 12377803
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: EDN1
Name: endothelin 1
Acc ID: GO:0005179
Term: hormone activity
Definition: The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
Definition Source(s): GOC:dph, GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EDN1enablesIBAPANTHER:PTN000356323 or UniProtKB:P05305 or UniProtKB:P14138 or UniProtKB:P20800150520179GO_Central GO_REF:0000033
EDN1enablesIEAPANTHER:PTHR13874:SF10150520179TreeGrafter GO_REF:0000118
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