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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12374086
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: JUN
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:26710
Term: sodium chloride
Definition: An inorganic chloride salt having sodium(1+) as the counterion.
Chemical ID: MESH:D012965
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNincreases expressionEXP 6480464CTDSodium Chloride results in increased expression of JUN proteinPMID:23816505
JUNmultiple interactionsEXP 6480464CTDpyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]; U 0126 inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]PMID:23816505
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