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GENE - TERM ANNOTATION REPORT

RGD ID: 12373160
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: DOID:9005643
Term: Experimental Diabetes Mellitus
Definition: Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Definition Source(s): MESH:D003921
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNF ISOTnf (Rattus norvegicus)9068941RGDprotein:increased expression:heartPMID:20555424 REF_RGD_ID:4142788
TNF ISOTnf (Rattus norvegicus)9068941RGDprotein:increased expression:liverPMID:21481476 REF_RGD_ID:5131250
TNFtreatmentISOTnf (Rattus norvegicus)9068941RGD PMID:19220660 PMID:24374093 REF_RGD_ID:10450575 REF_RGD_ID:2312478
TNF ISOTNF (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:12123627 PMID:12193562 PMID:19478208 PMID:20388520 PMID:22138235 PMID:24513509
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