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GENE - TERM ANNOTATION REPORT

RGD ID: 12355366
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CCL2
Name: C-C motif chemokine ligand 2
Acc ID: DOID:9007383
Term: Chemical and Drug Induced Liver Injury
Definition: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Definition Source(s): MESH:D056486
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2treatmentISOCcl2 (Mus musculus)9068941RGD PMID:21813474 PMID:30663942 REF_RGD_ID:14995458 REF_RGD_ID:14995466
CCL2 ISOCCL2 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:20623750
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