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GENE - TERM ANNOTATION REPORT

RGD ID: 12355366
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CCL2
Name: C-C motif chemokine ligand 2
Acc ID: DOID:3525
Term: middle cerebral artery infarction
Definition: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Definition Source(s): MESH:D020244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2 ISOCCL2 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:12374626 PMID:23043544 PMID:25257527
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