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GENE - TERM ANNOTATION REPORT

RGD ID: 12260125
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CASP8
Name: caspase 8
Acc ID: DOID:5082
Term: liver cirrhosis
Definition: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Definition Source(s): MESH:D008103
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP8 ISOCasp8 (Mus musculus)9068941RGDassociated with cholestasisPMID:29105510 REF_RGD_ID:13782297
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