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GENE - TERM ANNOTATION REPORT

RGD ID: 12244631
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: SH3PXD2B
Name: SH3 and PX domains 2B
Acc ID: GO:0002102
Term: podosome
Definition: An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
Definition Source(s): PMID:12837608, PMID:15890982
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SH3PXD2B ISORGD:13205339068941UniProtKB (MGI:MGI:4365313, PMID:19669234), (MGI:MGI:4943661, PMID:19144821)

MGI:MGI:4365313, MGI:MGI:4943661, PMID:19144821, PMID:19669234
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.