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GENE - TERM ANNOTATION REPORT

RGD ID: 12244446
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: EGR1
Name: early growth response 1
Acc ID: DOID:2349
Term: arteriosclerosis
Definition: An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Arteriosclerosis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGR1 ISOEgr1 (Mus musculus)9068941RGD PMID:14670837 REF_RGD_ID:5131652
EGR1 ISOEgr1 (Mus musculus)9068941RGDprotein:increased expression:atherosclerotic lesions, vascular associated smooth muscle cell, nucleus (mouse)PMID:21099169 REF_RGD_ID:5131874
EGR1 ISOEGR1 (Homo sapiens)9068941RGDmRNA, protein:increased expression:carotid artery, plaque (human)PMID:10712437 REF_RGD_ID:5131645
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