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GENE - TERM ANNOTATION REPORT

RGD ID: 12235618
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL4
Name: interleukin 4
Acc ID: DOID:9002850
Term: Immediate Hypersensitivity
Definition: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
Definition Source(s): MESH:D006969
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL4 ISOIL4 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:12755381 PMID:20485159 PMID:22967010
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