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RGD ID: 12222994
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CUL4A
Name: cullin 4A
Acc ID: GO:0080008
Term: Cul4-RING E3 ubiquitin ligase complex
Definition: A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Definition Source(s): PMID:16792691, PMID:18223036, PMID:18552200
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0033260, PANTHER:PTN000232236, UniProtKB:Q13619, UniProtKB:Q1362013508589GO_Central (PMID:21873635)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.