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GENE - TERM ANNOTATION REPORT

RGD ID: 12222722
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: DLA-DRB1
Name: MHC class II DLA DRB1 beta chain
Acc ID: DOID:7148
Term: rheumatoid arthritis
Definition: An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Rheumatoid_arthritis "DO" "DO", http://www.mayoclinic.org/diseases-conditions/rheumatoid-arthritis/home/ovc-20197388 "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/000431.htm "DO" "DO", http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=rheumatoid%20arthritis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DLA-DRB1 ISOHLA-DRB1 (Homo sapiens)9068941RGD PMID:18512783 REF_RGD_ID:4144826
DLA-DRB1 ISOHLA-DRB1 (Homo sapiens)9068941RGDDNA:polymorphism (human)PMID:11454644 REF_RGD_ID:5147860
DLA-DRB1 ISOHLA-DRB1 (Homo sapiens)9068941RGDDNA:polymorphisms (human)PMID:19117368 REF_RGD_ID:5147616
DLA-DRB1susceptibilityISOHLA-DRB1 (Homo sapiens)9068941RGDDNA:polymorphisms: :multiple (human)PMID:21246357 REF_RGD_ID:5147567
DLA-DRB1 ISOHLA-DRB1 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:19898480 PMID:20453842 PMID:22286218
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