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GENE - TERM ANNOTATION REPORT

RGD ID: 12199021
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: APP
Name: amyloid beta precursor protein
Acc ID: GO:0008021
Term: synaptic vesicle
Definition: A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
Definition Source(s): PMID:10099709, PMID:12563290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APPNOT|located_inISOApp (Rattus norvegicus)9068941AgBasePMID:8987743

PMID:8987743 REF_RGD_ID:8661630
APPlocated_inIEAUniProtKB:P12023 or ensembl:ENSMUSP00000154061150520179Ensembl GO_REF:0000107
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