Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 12198649
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CDK2
Name: cyclin dependent kinase 2
Acc ID: GO:0004693
Term: cyclin-dependent protein serine/threonine kinase activity
Definition: Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
Definition Source(s): GOC:pr, GOC:rn, PMID:7877684, PMID:9841670
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0004106|FB:FBgn0005640|FB:FBgn0013762|FB:FBgn0019949|FB:FBgn0263237|MGI:MGI:104772|MGI:MGI:88351|MGI:MGI:88357|PANTHER:PTN000623091|PomBase:SPAC23H4.17c|PomBase:SPAC2F3.15|PomBase:SPBC11B10.09|PomBase:SPBC19F8.07|PomBase:SPBC32H8.10|RGD:2319|RGD:621120|RGD:621124|RGD:70486|RGD:70514|SGD:S000000364|SGD:S000001622|SGD:S000005952|SGD:S000005963|SGD:S000006365|TAIR:locus:2011761|UniProtKB:A0A1D8PDA6|UniProtKB:C9K505|UniProtKB:O94921|UniProtKB:P06493|UniProtKB:P11802|UniProtKB:P24941|UniProtKB:P50750|UniProtKB:P61075|UniProtKB:Q00534|UniProtKB:Q00646|UniProtKB:Q8IJQ1|WB:WBGene00000405|ZFIN:ZDB-GENE-010131-2|dictyBase:DDB_G0272813|dictyBase:DDB_G028867713508589GO_Central PMID:21873635
 ISSRGD:13520109068941GO_Central PMID:21873635
 ISSRGD:13520109068941Reactome Reactome:R-HSA-174079, Reactome:R-HSA-187520, Reactome:R-HSA-187959, Reactome:R-HSA-188390, Reactome:R-HSA-3788705
 ISSRGD:13520109068941UniProtKB PMID:21596315
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.