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GENE - TERM ANNOTATION REPORT

RGD ID: 12192059
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:5844
Term: myocardial infarction
Definition: A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Myocardial_infarction "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/17951287 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1B ISOIl1b (Rattus norvegicus)9068941RGD PMID:23143013 REF_RGD_ID:7175553
IL1B ISOIl1b (Rattus norvegicus)9068941RGDprotein:increased expression:serum (rat)PMID:23237935 REF_RGD_ID:7204425
IL1BamelioratesISOIl1b (Rattus norvegicus)9068941RGD PMID:33389498 REF_RGD_ID:242905187
IL1B ISOIL1B (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:11743230 PMID:15883752 PMID:16310260
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