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GENE - TERM ANNOTATION REPORT

RGD ID: 12192059
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:2377
Term: multiple sclerosis
Definition: A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Multiple_sclerosis "DO" "DO", https://ghr.nlm.nih.gov/condition/multiple-sclerosis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1BseverityISOIL1B (Homo sapiens)9068941RGD PMID:10025794 REF_RGD_ID:1358741
IL1B ISOIL1B (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:15210533 PMID:25458313
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