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GENE - TERM ANNOTATION REPORT

RGD ID: 12187832
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: ACE
Name: angiotensin I converting enzyme
Acc ID: GO:0008237
Term: metallopeptidase activity
Definition: Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACE ISOAce (Rattus norvegicus)9068941RGD PMID:11299220 REF_RGD_ID:7401264
ACEenablesIEAUniProtKB:P09470 or UniProtKB:P12821 or ensembl:ENSMUSP00000001963 or ensembl:ENSP00000290866150520179Ensembl GO_REF:0000107
ACEenablesIEAInterPro:IPR001548150520179InterPro GO_REF:0000002
ACEenablesIEAPANTHER:PTHR10514:SF25 or PANTHER:PTHR10514:SF27150520179TreeGrafter GO_REF:0000118
ACEenablesIEAUniProtKB-KW:KW-0482150520179UniProt GO_REF:0000043
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