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GENE - TERM ANNOTATION REPORT

RGD ID: 12168136
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: TIGAR
Name: TP53 induced glycolysis regulatory phosphatase
Acc ID: GO:0006003
Term: fructose 2,6-bisphosphate metabolic process
Definition: The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TIGARinvolved_inIEAUniProtKB:Q8BZA9 or ensembl:ENSMUSP00000048643150520179Ensembl GO_REF:0000107
TIGARacts_upstream_of_or_withinISOTigar (Mus musculus)9068941MGI PMID:20935145

PMID:20935145
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