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GENE - TERM ANNOTATION REPORT

RGD ID: 12159133
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: LIPC
Name: lipase C, hepatic type
Acc ID: DOID:9970
Term: obesity
Definition: An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Obesity "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LIPC ISOLipc (Rattus norvegicus)9068941RGDprotein:altered expression:liver, plasma (rat)PMID:11544558 REF_RGD_ID:2308784
LIPC ISOLIPC (Homo sapiens)9068941RGDassociated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:plasma (human)PMID:12843191 REF_RGD_ID:2308835
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