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GENE - TERM ANNOTATION REPORT

RGD ID: 12109165
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CXCL10
Name: C-X-C motif chemokine ligand 10
Acc ID: DOID:2945
Term: severe acute respiratory syndrome
Definition: A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome "DO" "DO", http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=SARS "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL10 ISOCXCL10 (Homo sapiens)9068941RGDprotein:increased expression:serumPMID:17052299 REF_RGD_ID:5135440
CXCL10 ISOCXCL10 (Homo sapiens)9068941RGDprotein:increased expression:serum (human)PMID:15602737 REF_RGD_ID:32716399
CXCL10 ISOCxcl10 (Mus musculus)9068941RGDmRNA, protein: increased expression, altered expression:lung (mouse)PMID:15356152 REF_RGD_ID:30309221
CXCL10 ISOCxcl10 (Mus musculus)9068941RGDmRNA:increased expression:lung (mouse)PMID:32364527 REF_RGD_ID:27226699
CXCL10 ISOCxcl10 (Mus musculus)9068941RGDprotein:increased expression:lung (mouse)PMID:20231782 REF_RGD_ID:30309216
CXCL10disease_progressionISOCXCL10 (Homo sapiens)9068941RGDmRNA:decreased expression:lung (human)PMID:19635508 REF_RGD_ID:5490168
CXCL10severityISOCXCL10 (Homo sapiens)9068941RGDmRNA, protein:increased expression:plasma, lung (human)PMID:16195357 REF_RGD_ID:30309218
CXCL10severityISOCXCL10 (Homo sapiens)9068941RGDmRNA, protein:increased expression:serum, lung (human)PMID:15657466 REF_RGD_ID:30309219
CXCL10severityISOCXCL10 (Homo sapiens)9068941RGDprotein:increased expression:lung (human)PMID:17129463 REF_RGD_ID:30309217
CXCL10severityISOCxcl10 (Mus musculus)9068941RGDmRNA:increased expression:lung (mouse)PMID:32365944 REF_RGD_ID:30309207
CXCL10treatmentISOCXCL10 (Homo sapiens)9068941RGD PMID:15781938 PMID:15865221 REF_RGD_ID:30309220 REF_RGD_ID:33769580
CXCL10treatmentISOCxcl10 (Mus musculus)9068941RGD PMID:32553273 REF_RGD_ID:32716426
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