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GENE - TERM ANNOTATION REPORT

RGD ID: 12076607
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: LRRK2
Name: leucine rich repeat kinase 2
Acc ID: GO:0005515
Term: protein binding
Definition: Binding to a protein.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LRRK2enablesISOUniProtKB:Q141559068941BHF-UCL PMID:21048939

PMID:21048939
LRRK2enablesISOUniProtKB:Q9ES289068941BHF-UCL MGI:5318010 PMID:21048939

MGI:5318010 PMID:21048939
LRRK2enablesISOUniProtKB:Q9W5969068941BHF-UCL PMID:21159966

PMID:21159966
LRRK2enablesISOUniProtKB:O002039068941IntAct PMID:27424887

PMID:27424887
LRRK2enablesISOUniProtKB:O00203 or UniProtKB:P05141 or UniProtKB:P07195 or UniProtKB:P12235 or UniProtKB:P12236 or UniProtKB:P15880 or UniProtKB:P23396 or UniProtKB:P26373 or UniProtKB:P42677 or UniProtKB:P49207 or UniProtKB:P50914 or UniProtKB:P60866 or UniProtKB:P62249 or UniProtKB:P62258 or UniProtKB:P62266 or UniProtKB:P62269 or UniProtKB:P62277 or UniProtKB:P62280 or UniProtKB:P62750 or UniProtKB:P62841 or UniProtKB:P62888 or UniProtKB:P62906 or UniProtKB:Q8WUM09068941IntAct PMID:24725412

PMID:24725412
LRRK2enablesISOUniProtKB:O004299068941IntAct PMID:22228096 PMID:22639965

PMID:22228096 PMID:22639965
LRRK2enablesISOUniProtKB:O00429 or UniProtKB:O00429-39068941IntAct PMID:23813973

PMID:23813973
LRRK2enablesISOUniProtKB:O00429 or UniProtKB:O60313 or UniProtKB:O95140 or UniProtKB:P39053 or UniProtKB:Q05193 or UniProtKB:Q811U49068941IntAct PMID:24282027

PMID:24282027
LRRK2enablesISOUniProtKB:O00429 or UniProtKB:Q049179068941IntAct PMID:29541021

PMID:29541021
LRRK2enablesISOUniProtKB:O14640-2 or UniProtKB:O14641 or UniProtKB:Q929979068941IntAct PMID:19625296

PMID:19625296
LRRK2enablesISOUniProtKB:O14641 or UniProtKB:O15027 or UniProtKB:O43865 or UniProtKB:O55143 or UniProtKB:O60313 or UniProtKB:P04350 or UniProtKB:P07437 or UniProtKB:P15880 or UniProtKB:P21796 or UniProtKB:P23396 or UniProtKB:P26038 or UniProtKB:P26373 or UniProtKB:P27348 or UniProtKB:P30048 or UniProtKB:P30084 or UniProtKB:P31947 or UniProtKB:P42677 or UniProtKB:P49207 or UniProtKB:P49406 or UniProtKB:P60866 or UniProtKB:P61026 or UniProtKB:P62249 or UniProtKB:P62258 or UniProtKB:P62269 or UniProtKB:P62277 or UniProtKB:P62280 or UniProtKB:P62888 or UniProtKB:P62906 or UniProtKB:P63104 or UniProtKB:P63151 or UniProtKB:P68371 or UniProtKB:Q05639 or UniProtKB:Q12972 or UniProtKB:Q13885 or UniProtKB:Q4G0J3 or UniProtKB:Q53GS9 or UniProtKB:Q6P3X3 or UniProtKB:Q71RC2 or UniProtKB:Q8WUM0 or UniProtKB:Q99961 or UniProtKB:Q9BQ70 or UniProtKB:Q9BUF5 or UniProtKB:Q9H0U4 or UniProtKB:Q9UNE7 or UniProtKB:Q9Y6A49068941IntAct PMID:31046837

PMID:31046837
LRRK2enablesISOUniProtKB:O14733 or UniProtKB:P46734 or UniProtKB:P525649068941IntAct PMID:20067578

PMID:20067578
LRRK2enablesISOUniProtKB:O14966 or UniProtKB:O14976 or UniProtKB:O95816 or UniProtKB:O95817 or UniProtKB:P05060 or UniProtKB:P11142 or UniProtKB:P30084 or UniProtKB:P31946 or UniProtKB:P31947 or UniProtKB:P42679 or UniProtKB:P63104 or UniProtKB:Q12972 or UniProtKB:Q7L592 or UniProtKB:Q96PY6 or UniProtKB:Q9NQU5 or UniProtKB:Q9NWM3 or UniProtKB:Q9UL15 or UniProtKB:Q9UNE79068941IntAct PMID:24510904

PMID:24510904
LRRK2enablesISOUniProtKB:O14966 or UniProtKB:P57729 or UniProtKB:Q136379068941IntAct PMID:31552791

PMID:31552791
LRRK2enablesISOUniProtKB:O14976 or UniProtKB:O43865 or UniProtKB:O95218 or UniProtKB:O95816 or UniProtKB:P05060 or UniProtKB:P49406 or UniProtKB:Q13191 or UniProtKB:Q4G0J3 or UniProtKB:Q53GS9 or UniProtKB:Q6P3X3 or UniProtKB:Q71RC2 or UniProtKB:Q7L592 or UniProtKB:Q8N8V4 or UniProtKB:Q9NWM3 or UniProtKB:Q9UKI2 or UniProtKB:Q9UNE79068941IntAct PMID:29513927

PMID:29513927
LRRK2enablesISOUniProtKB:O14976 or UniProtKB:P05060 or UniProtKB:P07437 or UniProtKB:P11142 or UniProtKB:P27348 or UniProtKB:P30084 or UniProtKB:P31946 or UniProtKB:P42679 or UniProtKB:P60866 or UniProtKB:P61981 or UniProtKB:P62258 or UniProtKB:P62841 or UniProtKB:P63104 or UniProtKB:Q8N8V4 or UniProtKB:Q8WUM0 or UniProtKB:Q96PY6 or UniProtKB:Q9BQ70 or UniProtKB:Q9NQU5 or UniProtKB:Q9UKI2 or UniProtKB:Q9UL15 or UniProtKB:Q9Y6A49068941IntAct PMID:24947832

PMID:24947832
LRRK2enablesISOUniProtKB:O150279068941IntAct PMID:25201882

PMID:25201882
LRRK2enablesISOUniProtKB:O55143 or UniProtKB:P61982 or UniProtKB:P62259 or UniProtKB:P63101 or UniProtKB:P68254 or UniProtKB:P68510 or UniProtKB:Q9CQV89068941IntAct MGI:6355873 PMID:31046837

MGI:6355873 PMID:31046837
LRRK2enablesISOUniProtKB:O602609068941IntAct PMID:16352719

PMID:16352719
LRRK2enablesISOUniProtKB:O755819068941IntAct PMID:22899650 PMID:27013965

PMID:22899650 PMID:27013965
LRRK2enablesISOUniProtKB:O95218 or UniProtKB:P27348 or UniProtKB:P61981 or UniProtKB:P62258 or UniProtKB:P63104 or UniProtKB:Q04917 or UniProtKB:Q165439068941IntAct PMID:23075850

PMID:23075850
LRRK2enablesISOUniProtKB:O952959068941IntAct PMID:23949442

PMID:23949442
LRRK2enablesISOUniProtKB:P00634 or UniProtKB:P621369068941IntAct PMID:23937259

PMID:23937259
LRRK2enablesISOUniProtKB:P02687 or UniProtKB:P10636-89068941IntAct PMID:22303461

PMID:22303461
LRRK2enablesISOUniProtKB:P02687 or UniProtKB:P317499068941IntAct PMID:21658387

PMID:21658387
LRRK2enablesISOUniProtKB:P04350 or UniProtKB:P07437 or UniProtKB:P68371 or UniProtKB:Q13885 or UniProtKB:Q9BUF59068941IntAct PMID:24275654

PMID:24275654
LRRK2enablesISOUniProtKB:P05141 or UniProtKB:P12235 or UniProtKB:P12236 or UniProtKB:P21796 or UniProtKB:P302759068941IntAct PMID:21370995

PMID:21370995
LRRK2enablesISOUniProtKB:P10415-19068941IntAct PMID:25446991

PMID:25446991
LRRK2enablesISOUniProtKB:P10636-2 or UniProtKB:P10636-89068941IntAct PMID:24113872

PMID:24113872
LRRK2enablesISOUniProtKB:P111429068941IntAct PMID:23455607

PMID:23455607
LRRK2enablesISOUniProtKB:P11142 or UniProtKB:Q135019068941IntAct PMID:29519959

PMID:29519959
LRRK2enablesISOUniProtKB:P11142 or UniProtKB:Q9UKV89068941IntAct PMID:17400507

PMID:17400507
LRRK2enablesISOUniProtKB:P12369 or UniProtKB:P176129068941IntAct PMID:24464040

PMID:24464040
LRRK2enablesISOUniProtKB:P17612 or UniProtKB:P26038 or UniProtKB:P27348 or UniProtKB:P61983 or UniProtKB:P631049068941IntAct PMID:24351927

PMID:24351927
LRRK2enablesISOUniProtKB:P260389068941IntAct MGI:5586773 PMID:24794857

MGI:5586773 PMID:24794857
LRRK2enablesISOUniProtKB:P260389068941IntAct PMID:22952686 PMID:23241358 PMID:24695735 PMID:24904275 PMID:25009464 PMID:27357661

PMID:22952686 PMID:23241358 PMID:24695735 PMID:24904275 PMID:25009464 PMID:27357661
LRRK2enablesISOUniProtKB:P26038 or UniProtKB:P27348 or UniProtKB:P31946 or UniProtKB:P61981 or UniProtKB:P62258 or UniProtKB:P63104 or UniProtKB:Q04917 or UniProtKB:Q165439068941IntAct PMID:20642453

PMID:20642453
LRRK2enablesISOUniProtKB:P26038 or UniProtKB:P61006 or UniProtKB:P61026 or UniProtKB:P62841 or UniProtKB:Q6IQ22 or UniProtKB:Q9H0U49068941IntAct PMID:26824392

PMID:26824392
LRRK2enablesISOUniProtKB:P26038 or UniProtKB:Q62848 or UniProtKB:Q8N6T3-29068941IntAct PMID:22363216

PMID:22363216
LRRK2enablesISOUniProtKB:P300489068941IntAct PMID:21850687 PMID:24459295

PMID:21850687 PMID:24459295
LRRK2enablesISOUniProtKB:P313249068941IntAct MGI:5553024 PMID:24464040

MGI:5553024 PMID:24464040
LRRK2enablesISOUniProtKB:P31947 or UniProtKB:P619819068941IntAct PMID:28202711

PMID:28202711
LRRK2enablesISOUniProtKB:P378409068941IntAct PMID:23183827

PMID:23183827
LRRK2enablesISOUniProtKB:P390539068941IntAct PMID:21307259 PMID:24687852

PMID:21307259 PMID:24687852
LRRK2enablesISOUniProtKB:P412209068941IntAct PMID:24794857

PMID:24794857
LRRK2enablesISOUniProtKB:P464609068941IntAct MGI:4941068 PMID:21307259 MGI:5568145 PMID:24687852

MGI:4941068 MGI:5568145 PMID:21307259 PMID:24687852
LRRK2enablesISOUniProtKB:P46734 or UniProtKB:Q58A659068941IntAct PMID:20173330

PMID:20173330
LRRK2enablesISOUniProtKB:P46821-PRO_00000186059068941IntAct PMID:24754922

PMID:24754922
LRRK2enablesISOUniProtKB:P48729-1 or UniProtKB:Q141559068941IntAct PMID:25500533

PMID:25500533
LRRK2enablesISOUniProtKB:P48730-2 or UniProtKB:P60896 or UniProtKB:Q13191 or UniProtKB:Q8NHS9 or UniProtKB:Q9BUL99068941IntAct PMID:32814053

PMID:32814053
LRRK2enablesISOUniProtKB:P498419068941IntAct PMID:24165324

PMID:24165324
LRRK2enablesISOUniProtKB:P53355 or UniProtKB:Q38SD29068941IntAct PMID:19712061

PMID:19712061
LRRK2enablesISOUniProtKB:P60953 or UniProtKB:P630009068941IntAct PMID:21454543

PMID:21454543
LRRK2enablesISOUniProtKB:P60953 or UniProtKB:Q141559068941IntAct PMID:21048939

PMID:21048939
LRRK2enablesISOUniProtKB:P610069068941IntAct PMID:32017888

PMID:32017888
LRRK2enablesISOUniProtKB:P610209068941IntAct PMID:25605758 PMID:27314038

PMID:25605758 PMID:27314038
LRRK2enablesISOUniProtKB:P61020 or UniProtKB:P610219068941IntAct PMID:18445495

PMID:18445495
LRRK2enablesISOUniProtKB:P61982 or UniProtKB:P62259 or UniProtKB:P63101 or UniProtKB:P68254 or UniProtKB:P68510 or UniProtKB:Q9CQV89068941IntAct MGI:5487519 PMID:21390248

MGI:5487519 PMID:21390248
LRRK2enablesISOUniProtKB:P631519068941IntAct PMID:26894577

PMID:26894577
LRRK2enablesISOUniProtKB:Q056399068941IntAct PMID:19559761

PMID:19559761
LRRK2enablesISOUniProtKB:Q131589068941IntAct PMID:19176810

PMID:19176810
LRRK2enablesISOUniProtKB:Q134699068941IntAct PMID:21983832

PMID:21983832
LRRK2enablesISOUniProtKB:Q136379068941IntAct PMID:25360523

PMID:25360523
LRRK2enablesISOUniProtKB:Q165439068941IntAct PMID:16321986 PMID:22612223

PMID:16321986 PMID:22612223
LRRK2enablesISOUniProtKB:Q38SD29068941IntAct PMID:20144646

PMID:20144646
LRRK2enablesISOUniProtKB:Q634819068941IntAct PMID:23395371

PMID:23395371
LRRK2enablesISOUniProtKB:Q8K1M69068941IntAct MGI:5431272 PMID:22639965 MGI:5538411 PMID:24282027 MGI:6355691 PMID:29541021

MGI:5431272 MGI:5538411 MGI:6355691 PMID:22639965 PMID:24282027 PMID:29541021
LRRK2enablesISOUniProtKB:Q99961 or UniProtKB:Q999629068941IntAct PMID:22998870

PMID:22998870
LRRK2enablesISOUniProtKB:Q999629068941IntAct PMID:25501810

PMID:25501810
LRRK2enablesISOUniProtKB:Q9EPJ99068941IntAct MGI:5318636 PMID:22363216

MGI:5318636 PMID:22363216
LRRK2enablesISOUniProtKB:Q9UKV89068941IntAct PMID:20671708

PMID:20671708
LRRK2enablesISOUniProtKB:Q9ULV49068941IntAct PMID:33938021

PMID:33938021
LRRK2enablesISOUniProtKB:Q9UNE7-1 or UniProtKB:Q9WUD19068941IntAct PMID:19196961

PMID:19196961
LRRK2enablesISOUniProtKB:Q9Y6I79068941IntAct PMID:27273569

PMID:27273569
LRRK2enablesISOPR:O549279068941MGI PMID:27273569

PMID:27273569
LRRK2enablesISOPR:Q5NCX59068941MGI PMID:26355680

PMID:26355680
LRRK2enablesISOPR:Q8CI32 or PR:Q91YQ19068941MGI PMID:24510904

PMID:24510904
LRRK2enablesISOPR:Q9EPJ99068941MGI PMID:22423108

PMID:22423108
LRRK2enablesISOUniPRotKB:O888959068941MGI PMID:27798112

PMID:27798112
LRRK2enablesISOUniProtKB:O35643 or UniProtKB:O88935 or UniProtKB:P17426 or UniProtKB:P17427 or UniProtKB:P39053 or UniProtKB:Q61548 or UniProtKB:Q80TJ1 or UniProtKB:Q9JIS59068941ParkinsonsUK-UCL PMID:21307259

PMID:21307259
LRRK2enablesISOUniProtKB:P51141 or UniProtKB:Q610629068941ParkinsonsUK-UCL MGI:5440351 PMID:22899650

MGI:5440351 PMID:22899650
LRRK2enablesISOUniProtKB:Q13387 or UniProtKB:Q9ESN9 or UniProtKB:Q9WVI99068941ParkinsonsUK-UCL PMID:20173330

PMID:20173330
LRRK2enablesISOUniProtKB:Q9EQH39068941ParkinsonsUK-UCL MGI:5784974 PMID:23395371

MGI:5784974 PMID:23395371
LRRK2enablesISOUniProtKB:E9QAT49068941UniProt MGI:5608715 PMID:25201882

MGI:5608715 PMID:25201882
LRRK2enablesISOUniProtKB:P050679068941UniProt MGI:6142520 PMID:28720718

MGI:6142520 PMID:28720718
LRRK2enablesISOUniProtKB:P050679068941UniProt PMID:28720718

PMID:28720718
LRRK2enablesISOUniProtKB:P106369068941UniProt PMID:26014385

PMID:26014385
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