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GENE - TERM ANNOTATION REPORT

RGD ID: 12075753
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CDC42EP3
Name: CDC42 effector protein 3
Acc ID: GO:0005856
Term: cytoskeleton
Definition: Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Definition Source(s): GOC:mah, ISBN:0198547684, PMID:16959967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDC42EP3 IBAPANTHER:PTN001034302 UniProtKB:O14613 UniProtKB:Q9H3Q1 UniProtKB:Q9UKI213508589GO_Central PMID:21873635

PMID:21873635
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