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GENE - TERM ANNOTATION REPORT

RGD ID: 12075184
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: FAS
Name: Fas cell surface death receptor
Acc ID: GO:0031265
Term: CD95 death-inducing signaling complex
Definition: A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.
Definition Source(s): PMID:12628743, PMID:12655293
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FAS ISOFas (Rattus norvegicus)9068941RGD PMID:16493077 REF_RGD_ID:4143200
FASpart_ofIEAPANTHER:PTHR46874:SF1150520179TreeGrafter GO_REF:0000118
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