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GENE - TERM ANNOTATION REPORT

RGD ID: 12008550
Species: Pan paniscus
RGD Object: Gene
Symbol: MMP9
Name: matrix metallopeptidase 9
Acc ID: DOID:6432
Term: pulmonary hypertension
Definition: A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Pulmonary_hypertension "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/19555858 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP9 ISOMMP9 (Homo sapiens)9068941RGD PMID:21063214 REF_RGD_ID:5129210
MMP9 ISOMMP9 (Homo sapiens)9068941RGDassociated with Heart Failure, Congestive;protein:decreased expression:monocytePMID:16867026 REF_RGD_ID:1642028
MMP9 ISOMmp9 (Rattus norvegicus)9068941RGD PMID:23087098 REF_RGD_ID:7207217
MMP9 ISOMmp9 (Rattus norvegicus)9068941RGDassociated with Pulmonary Embolism;protein:increased expression:lung, plasmaPMID:17133179 REF_RGD_ID:1642053
MMP9severityISOMMP9 (Homo sapiens)9068941RGD PMID:18355767 REF_RGD_ID:5130155
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