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GENE - TERM ANNOTATION REPORT

RGD ID: 12000872
Species: Pan paniscus
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:9005372
Term: Inflammation
Definition: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Definition Source(s): MESH:D007249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1B ISOIl1b (Rattus norvegicus)9068941RGDassociated with AnoxiaPMID:22994521 REF_RGD_ID:7204492
IL1B ISOIl1b (Rattus norvegicus)9068941RGDassociated with Cholestasis;mRNA:increased expression:liverPMID:17676395 REF_RGD_ID:1626645
IL1B ISOIl1b (Rattus norvegicus)9068941RGDassociated with Hypersensitivity, Delayed;protein:increased expression:brain, plasmaPMID:15050649 REF_RGD_ID:1626679
IL1BtreatmentISOIl1b (Rattus norvegicus)9068941RGD PMID:25706245 PMID:26069367 REF_RGD_ID:11059519 REF_RGD_ID:11059520
IL1B ISOIL1B (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:11181422 PMID:16227999 PMID:21437948 PMID:21467745 PMID:22001142 PMID:23640035 PMID:24609059 PMID:28212736 PMID:9952427
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