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GENE - TERM ANNOTATION REPORT

RGD ID: 12000872
Species: Pan paniscus
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:1596
Term: depressive disorder
Definition: A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function. (DO)
Definition Source(s): https://my.clevelandclinic.org/health/diseases/9290-depression "DO" "DO", https://pubmed.ncbi.nlm.nih.gov/31550874/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1B ISOIl1b (Mus musculus)9068941RGDprotein:increased expression:serum, hippocampus (mouse)PMID:31396300 REF_RGD_ID:126908003
IL1B ISOIl1b (Rattus norvegicus)9068941RGDprotein:increased expression:frontal cortex, hippocampus, hypothalamus (rat)PMID:15000880 REF_RGD_ID:1626681
IL1B ISOIL1B (Homo sapiens)9068941RGDassociated with gastric adenocarcinoma; protein:increased expression:blood serum (human)PMID:31396300 REF_RGD_ID:126908003
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