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GENE - TERM ANNOTATION REPORT

RGD ID: 12000872
Species: Pan paniscus
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:10763
Term: hypertension
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Hypertension "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/24352797 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1B ISOIl1b (Rattus norvegicus)9068941RGD PMID:21173343 REF_RGD_ID:7175338
IL1B ISOIl1b (Rattus norvegicus)9068941RGDmRNA, protein:increased expression:aorta, plasmaPMID:15894892 REF_RGD_ID:1626635
IL1B ISOIL1B (Homo sapiens)9068941RGDassociated with Obesity;protein:increased expression:plasmaPMID:15990729 REF_RGD_ID:1626638
IL1B ISOIL1B (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127
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