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GENE - TERM ANNOTATION REPORT

RGD ID: 12000872
Species: Pan paniscus
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: DOID:10126
Term: keratoconus
Definition: A corneal disease characterized by structural changes within the cornea causing it to thin and change, leading to a protruding conical shape. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Keratoconus "DO" "DO", http://ghr.nlm.nih.gov/glossary=keratoconus "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1B ISOIL1B (Homo sapiens)9068941RGDDNA:SNPs, haplotype:promoter:-31T>C (rs1143627), -511C>T (rs16944) (human)PMID:23592922 REF_RGD_ID:7401165
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