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GENE - TERM ANNOTATION REPORT

RGD ID: 11974812
Species: Pan paniscus
RGD Object: Gene
Symbol: IDO1
Name: indoleamine 2,3-dioxygenase 1
Acc ID: DOID:9005930
Term: Endotoxemia
Definition: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
Definition Source(s): MESH:D019446
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IDO1 ISOIdo1 (Mus musculus)9068941RGD PMID:24930766 PMID:28077574 REF_RGD_ID:39939032 REF_RGD_ID:39939117
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