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GENE - TERM ANNOTATION REPORT

RGD ID: 11966443
Species: Pan paniscus
RGD Object: Gene
Symbol: CLDN5
Name: claudin 5
Acc ID: GO:0005923
Term: bicellular tight junction
Definition: An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
Definition Source(s): GOC:mah, ISBN:0815332181
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CLDN5located_inIEAUniProtKB:O54942 or ensembl:ENSMUSP00000041925150520179Ensembl GO_REF:0000107
CLDN5located_inIEAInterPro:IPR003551 or InterPro:IPR006187150520179InterPro GO_REF:0000002
CLDN5located_inIEAPANTHER:PTHR12002:SF35150520179TreeGrafter GO_REF:0000118
CLDN5located_inIEAUniProtKB-KW:KW-0796150520179UniProt GO_REF:0000043
CLDN5located_inIEAUniProtKB-SubCell:SL-0265150520179UniProt GO_REF:0000044
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