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GENE - TERM ANNOTATION REPORT

RGD ID: 11949981
Species: Pan paniscus
RGD Object: Gene
Symbol: PTPN11
Name: protein tyrosine phosphatase non-receptor type 11
Acc ID: DOID:9007033
Term: Ventricular Premature Complexes
Definition: A type of cardiac arrhythmia with premature contractions of the HEART VENTRICLES. It is characterized by the premature QRS complex on ECG that is of abnormal shape and great duration (generally >129 msec). It is the most common form of all cardiac arrhythmias. Premature ventricular complexes have no clinical significance except in concurrence with heart diseases.
Definition Source(s): MESH:D018879
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTPN11 ISOPTPN11 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Premature ventricular contractionPMID:23334666 PMID:25741868 PMID:26223499 PMID:28492532
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