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GENE - TERM ANNOTATION REPORT

RGD ID: 11903814
Species: Pan paniscus
RGD Object: Gene
Symbol: CCL2
Name: C-C motif chemokine ligand 2
Acc ID: DOID:8947
Term: diabetic retinopathy
Definition: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
Definition Source(s): MESH:D003930
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2 ISOCcl2 (Rattus norvegicus)9068941RGDassociated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:retina (rat)PMID:23010641 REF_RGD_ID:8548887
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