Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

RGD ID: 11885058
Species: Pan paniscus
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: DOID:1485
Term: cystic fibrosis
Definition: A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Cystic_fibrosis "DO" "DO", http://ghr.nlm.nih.gov/condition/cystic-fibrosis "DO" "DO", http://www.nhlbi.nih.gov/health/health-topics/topics/cf/ "DO" "DO", https://www.genome.gov/Genetic-Disorders/Cystic-Fibrosis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNF ISOTNF (Homo sapiens)9068941RGDprotein:increased expression:sputumPMID:7537567 REF_RGD_ID:4142846
TNFseverityISOTNF (Homo sapiens)9068941RGDDNA:polymorphism, haplotype:promoter:−308G>A (rs1800629) (human)PMID:21993476 REF_RGD_ID:6767553
Go Back to source page   Continue to Ontology report