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GENE - TERM ANNOTATION REPORT

RGD ID: 11830446
Species: Pan paniscus
RGD Object: Gene
Symbol: UBQLN2
Name: ubiquilin 2
Acc ID: DOID:332
Term: amyotrophic lateral sclerosis
Definition: A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Amyotrophic_lateral_sclerosis "DO" "DO", http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_ALS.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UBQLN2 ISOUBQLN2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Lou Gehrig diseasePMID:21857683 PMID:25333069 PMID:25616961 PMID:25741868 PMID:26075709 PMID:28492532
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