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GENE - TERM ANNOTATION REPORT

RGD ID: 11812651
Species: Pan paniscus
RGD Object: Gene
Symbol: JUP
Name: junction plakoglobin
Acc ID: GO:0005912
Term: adherens junction
Definition: A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
Definition Source(s): GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:17854762, PMID:20571587, PMID:21422226, PMID:28096264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUP ISOJup (Rattus norvegicus)9068941RGD PMID:8834786 REF_RGD_ID:2291902
JUPlocated_inIEAUniProtKB:P14923 or UniProtKB:Q02257 or ensembl:ENSMUSP00000001592 or ensembl:ENSP00000377508150520179Ensembl GO_REF:0000107
JUPlocated_inIEAPANTHER:PTHR45976:SF3150520179TreeGrafter GO_REF:0000118
JUPlocated_inIEAARBA:ARBA00028426150520179UniProt GO_REF:0000117
JUPlocated_inIEAUniProtKB-SubCell:SL-0009150520179UniProt GO_REF:0000044
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