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GENE - TERM ANNOTATION REPORT

RGD ID: 11785447
Species: Pan paniscus
RGD Object: Gene
Symbol: APOE
Name: apolipoprotein E
Acc ID: GO:0034363
Term: intermediate-density lipoprotein particle
Definition: A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).
Definition Source(s): GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APOEpart_ofIEAUniProtKB:P02649 or ensembl:ENSP00000252486150520179Ensembl GO_REF:0000107
APOEpart_ofIEAPANTHER:PTHR18976:SF2150520179TreeGrafter GO_REF:0000118
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