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GENE - TERM ANNOTATION REPORT

RGD ID: 11775376
Species: Pan paniscus
RGD Object: Gene
Symbol: TKT
Name: transketolase
Acc ID: GO:0006098
Term: pentose-phosphate shunt
Definition: The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).
Definition Source(s): GOC:pde, ISBN:0198506732, MetaCyc:PENTOSE-P-PWY
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TKT ISOTkt (Rattus norvegicus)9068941RGD PMID:2843500 REF_RGD_ID:1599574
TKTinvolved_inIEAUniProtKB:P29401 or UniProtKB:P40142 or ensembl:ENSMUSP00000022529 or ensembl:ENSP00000417773150520179Ensembl GO_REF:0000107
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