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GENE - TERM ANNOTATION REPORT

RGD ID: 11771717
Species: Pan paniscus
RGD Object: Gene
Symbol: SMPD1
Name: sphingomyelin phosphodiesterase 1
Acc ID: GO:0005764
Term: lysosome
Definition: A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
Definition Source(s): GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SMPD1located_inIEAPANTHER:PTHR10340:SF34150520179TreeGrafter GO_REF:0000118
SMPD1is_active_inISOSMPD1 (Homo sapiens)9068941UniProt PMID:33163980

PMID:33163980
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