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GENE - TERM ANNOTATION REPORT

RGD ID: 11683512
Species: Pan paniscus
RGD Object: Gene
Symbol: CYP46A1
Name: cytochrome P450 family 46 subfamily A member 1
Acc ID: GO:0033781
Term: cholesterol 24-hydroxylase activity
Definition: Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+.
Definition Source(s): EC:1.14.14.25, RHEA:22716
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP46A1enablesIEAUniProtKB:Q9WVK8 or UniProtKB:Q9Y6A2 or ensembl:ENSMUSP00000021684 or ensembl:ENSP00000261835150520179Ensembl GO_REF:0000107
CYP46A1enablesIEAInterPro:IPR039983150520179InterPro GO_REF:0000002
CYP46A1enablesIEAPANTHER:PTHR24293:SF1150520179TreeGrafter GO_REF:0000118
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